HDAC1 Inactivation Induces Mitotic Defect and Caspase-Independent Autophagic Cell Death in Liver Cancer

Histone deacetylases (HDACs) are known to play a central role in the regulation of several cellular properties interlinked with the development and progression of cancer. Recently, HDAC1 has been reported to be overexpressed in hepatocellular carcinoma (HCC), but its biological roles in hepatocarcin...

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Autores principales: Xie, Hong Jian, Noh, Ji Heon, Kim, Jeong Kyu, Jung, Kwang Hwa, Eun, Jung Woo, Bae, Hyun Jin, Kim, Min Gyu, Chang, Young Gyoon, Lee, Jung Young, Park, Hanna, Nam, Suk Woo
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319574/
https://ncbi.nlm.nih.gov/pubmed/22496786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034265
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