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Aberrant Regulation of HDAC2 Mediates Proliferation of Hepatocellular Carcinoma Cells by Deregulating Expression of G1/S Cell Cycle Proteins

Histone deacetylase 2 (HDAC2) is crucial for embryonic development, affects cytokine signaling relevant for immune responses and is often significantly overexpressed in solid tumors; but little is known about its role in human hepatocellular carcinoma (HCC). In this study, we showed that targeted-di...

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Detalhes bibliográficos
Main Authors: Noh, Ji Heon, Jung, Kwang Hwa, Kim, Jeong Kyu, Eun, Jung Woo, Bae, Hyun Jin, Xie, Hong Jian, Chang, Young Gyoon, Kim, Min Gyu, Park, Won Sang, Lee, Jung Young, Nam, Suk Woo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223227/
https://ncbi.nlm.nih.gov/pubmed/22132221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028103
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