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Dietary Choline Deficiency causes DNA Strand Breaks and Alters Epigenetic Marks on DNA and Histones
Dietary choline is an important modulator of gene expression (via epigenetic marks) and of DNA integrity. Choline was discovered to be an essential nutrient for some humans approximately one decade ago. This requirement is diminished in young women because estrogen drives endogenous synthesis of pho...
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| Format: | Artigo |
| Jezik: | Inglês |
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2011
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319504/ https://ncbi.nlm.nih.gov/pubmed/22041500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2011.10.008 |
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