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Hsp90 inhibitor 17-AAG inhibits progression of LuCaP35 xenograft prostate tumors to castration resistance

BACKGROUND: Advanced prostate cancer is currently treated with androgen deprivation therapy (ADT). ADT initially results in tumor regression, however, all patients eventually relapse with castration-resistant prostate cancer. New approaches to delay the progression of prostate cancer to castration r...

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Main Authors: O’Malley, Katherine J., Langmann, Gabrielle, Ai, Junkui, Ramos-Garcia, Raquel, Vessella, Robert L., Wang, Zhou
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319476/
https://ncbi.nlm.nih.gov/pubmed/22161776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22458
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