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Structural and functional analysis of temperature-sensitive mutants of the phage phi 29 DNA polymerase.

The cloning and complete sequencing of gene 2 from four independently isolated temperature-sensitive mutants in the phage phi 29 DNA polymerase (ts2 mutants) is reported. The results obtained indicate that, in vivo, the mutations only affect the initial steps of the replication process. Interestingl...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Blasco, M A, Blanco, L, Parés, E, Salas, M, Bernad, A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1990
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2118623/
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