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Structural and functional analysis of temperature-sensitive mutants of the phage phi 29 DNA polymerase.
The cloning and complete sequencing of gene 2 from four independently isolated temperature-sensitive mutants in the phage phi 29 DNA polymerase (ts2 mutants) is reported. The results obtained indicate that, in vivo, the mutations only affect the initial steps of the replication process. Interestingl...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1990
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC331939/ https://ncbi.nlm.nih.gov/pubmed/2118623 |
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