Dense Genotyping of Candidate Gene Loci Identifies Variants Associated with High-Density Lipoprotein Cholesterol

BACKGROUND: Plasma levels of high density lipoprotein cholesterol (HDL-C) are known to be heritable, but only a fraction of the heritability is explained. We used a high density genotyping array containing SNPs from HDL-C candidate genes selected on known biology of HDL-C metabolism, mouse genetic s...

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Autors principals: Edmondson, Andrew C., Braund, Peter S., Stylianou, Ioannis M., Khera, Amit V., Nelson, Christopher P., Wolfe, Megan L., DerOhannessian, Stephanie L., Keating, Brendan J., Qu, Liming, He, Jing, Tobin, Martin D., Tomaszewski, Maciej, Baumert, Jens, Klopp, Norman, Döring, Angela, Thorand, Barbara, Li, Mingyao, Reilly, Muredach P., Koenig, Wolfgang, Samani, Nilesh J., Rader, Daniel J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319351/
https://ncbi.nlm.nih.gov/pubmed/21303902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.110.957563
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