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Induced Regulatory T cells: Mechanisms of Conversion and Suppressive Potential

Thymus-derived, naturally-occurring CD4(+) FoxP3(+) regulatory T cells (nTreg) have suppressive activity that is important for the establishment and maintenance of immune homeostasis in the healthy state. Abundant reports have shown that they can suppress pathogenic processes in autoimmune diseases...

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Autors principals: Dons, Eefje M., Raimondi, Giorgio, Cooper, David K.C., Thomson, Angus W.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319286/
https://ncbi.nlm.nih.gov/pubmed/22285847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2011.12.011
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