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Induced Regulatory T cells: Mechanisms of Conversion and Suppressive Potential

Thymus-derived, naturally-occurring CD4(+) FoxP3(+) regulatory T cells (nTreg) have suppressive activity that is important for the establishment and maintenance of immune homeostasis in the healthy state. Abundant reports have shown that they can suppress pathogenic processes in autoimmune diseases...

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Detalhes bibliográficos
Main Authors: Dons, Eefje M., Raimondi, Giorgio, Cooper, David K.C., Thomson, Angus W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319286/
https://ncbi.nlm.nih.gov/pubmed/22285847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2011.12.011
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