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Cysteines control the N- and C-linker-dependent gating of KCNH1 potassium channels

KCNH1 (EAG1) is a member of the Kv family of voltage-gated potassium channels. However, KCNH1 channels also show some amino-acid sequence similarity to cyclic-nucleotide-regulated channels: they harbor an N-terminal PAS domain, a C-terminal cyclic nucleotide binding homology domain (cNBHD), and N- a...

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Detalhes bibliográficos
Main Authors: Sahoo, Nirakar, Schönherr, Roland, Hoshi, Toshinori, Heinemann, Stefan H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319268/
https://ncbi.nlm.nih.gov/pubmed/22310694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2012.01.021
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