RNA-binding protein HuD controls insulin translation

Although expression of the mammalian RNA-binding protein HuD was considered to be restricted to neurons, we report that HuD is present in pancreatic β cells, where its levels are controlled by the insulin receptor pathway. We found that HuD associated with a 22-nucleotide segment of the 5'-untr...

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Detalhes bibliográficos
Main Authors: Lee, Eun Kyung, Kim, Wook, Tominaga, Kumiko, Martindale, Jennifer L., Yang, Xiaoling, Subaran, Sarah S., Carlson, Olga D., Mercken, Evi M., Kulkarni, Rohit N., Akamatsu, Wado, Okano, Hideyuki, Perrone-Bizzozero, Nora I., de Cabo, Rafael, Egan, Josephine M., Gorospe, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319250/
https://ncbi.nlm.nih.gov/pubmed/22387028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.01.016
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