Comparison of Efficacy and Safety of Leptin Replacement Therapy in Moderately and Severely Hypoleptinemic Patients with Familial Partial Lipodystrophy of the Dunnigan Variety

CONTEXT: Leptin replacement therapy improves metabolic complications in patients with lipodystrophy and severe hypoleptinemia (SH), but whether the response is related to the degree of hypoleptinemia remains unclear. OBJECTIVE: The aim of the study was to compare efficacy of leptin therapy in famili...

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Detalhes bibliográficos
Main Authors: Simha, Vinaya, Subramanyam, Lalitha, Szczepaniak, Lidia, Quittner, Claudia, Adams-Huet, Beverley, Snell, Peter, Garg, Abhimanyu
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Endocrine Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319219/
https://ncbi.nlm.nih.gov/pubmed/22170723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-2229
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