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Establishing Rps6 hemizygous mice as a model for studying how ribosomal protein haploinsufficiency impairs erythropoiesis
Diamond-Blackfan Anemia(DBA) is a congenital hypoproliferative macrocytic anemia; 5q-syndrome myelodysplastic syndrome(MDS) is an acquired hypoproliferative macrocytic anemia. Their common erythroid phenotype reflects a shared pathophysiology -- haploinsufficiency of one of many ribosomal proteins a...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3319152/ https://ncbi.nlm.nih.gov/pubmed/22198155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2011.12.003 |
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