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Probing Na(+) Induced Changes in the HIV-1 TAR Conformational Dynamics using NMR Residual Dipolar Couplings: New Insights into the Role of Counterions and Electrostatic Interactions in Adaptive Recognition()

Many regulatory RNAs undergo large changes in structure upon recognition of proteins and ligands but the mechanism by which this occur remains poorly understood. Using NMR residual dipolar coupling (RDCs), we characterized Na(+) induced changes in the structure and dynamics of the bulge-containing H...

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Autori principali: Casiano-Negroni, Anette, Sun, Xiaoyan, Al-Hashimi, Hashim M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319146/
https://ncbi.nlm.nih.gov/pubmed/17488097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700335n
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