Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu(4)) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu(4) positive allosteric modulator

Lignende værker

• Solution-Phase Parallel Synthesis and SAR of Homopiperazinyl Analogs as Positive Allosteric Modulators of mGlu(4)
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  Udgivet: (2011)
• Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu(4))
  af: Gogliotti, Rocco D., et al.
  Udgivet: (2016)
• Challenges in the Discovery and Optimization of mGlu(2/4) Heterodimer Positive Allosteric Modulators
  af: Fulton, Mark Gallant, et al.
  Udgivet: (2019)
• Antidepressant potential of metabotropic glutamate receptor mGlu(2) and mGlu(3) negative allosteric modulators
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  Udgivet: (2018)
• mGluR4-positive allosteric modulation as potential treatment for Parkinson’s disease
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  Udgivet: (2009)