Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma

Activating mutations in the anaplastic lymphoma kinase (ALK) gene were recently discovered in neuroblastoma, a cancer of the developing autonomic nervous system that is the most commonly diagnosed malignancy in the first year of life. The most frequent ALK mutations in neuroblastoma cause amino acid...

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Detalhes bibliográficos
Main Authors: Bresler, Scott C., Wood, Andrew C., Haglund, Elizabeth A., Courtright, Joshua, Belcastro, Lili T., Plegaria, Jefferson S., Cole, Kristina, Toporovskaya, Yana, Zhao, Huaqing, Carpenter, Erica L., Christensen, James G., Maris, John M., Lemmon, Mark A., Mossé, Yaël P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319004/
https://ncbi.nlm.nih.gov/pubmed/22072639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002950
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