Circulating Myeloid-Derived Suppressor Cells Are Increased and Activated in Pulmonary Hypertension

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) are increased in inflammatory and autoimmune disorders and orchestrate immune cell responses therein. Pulmonary hypertension (PH) is associated with inflammation, autoimmunity, and lung vascular remodeling. Immature myeloid cells are found in the...

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Autors principals: Yeager, Michael E., Nguyen, Cecilia M., Belchenko, Dmitry D., Colvin, Kelley L., Takatsuki, Shinichi, Ivy, D. Dunbar, Stenmark, Kurt R.
Format: Artigo
Idioma:Inglês
Publicat: American College of Chest Physicians 2012
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318947/
https://ncbi.nlm.nih.gov/pubmed/21940769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1378/chest.11-0205
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