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Endothelin-1, the Unfolded Protein Response, and Persistent Inflammation: Role of Pulmonary Artery Smooth Muscle Cells

Endothelin-1 is a potent vasoactive peptide that occurs in chronically high levels in humans with pulmonary hypertension and in animal models of the disease. Recently, the unfolded protein response was implicated in a variety of diseases, including pulmonary hypertension. In addition, evidence is in...

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Detalhes bibliográficos
Main Authors: Yeager, Michael E., Belchenko, Dmitry D., Nguyen, Cecilia M., Colvin, Kelley L., Ivy, D. Dunbar, Stenmark, K. R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262656/
https://ncbi.nlm.nih.gov/pubmed/21778413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2010-0506OC
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