Mineralocorticoid Receptor Blocker Protects against Podocyte-Dependent Glomerulosclerosis

BACKGROUND: We previously showed that angiotensin type 1 receptor (AT1) blocker (ARB) attenuates glomerular injury in Nphs1-hCD25 (NEP25) transgenic mice, a model of selective podocyte injury. However, subsequent studies in NEP25 mice with podocyte-specific deficiency of AT1 revealed that the protec...

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Bibliografiske detaljer
Main Authors: Takagi, Nobuaki, Tanizawa, Takakuni, Kon, Valentina, Fogo, Agnes B., Ichikawa, Iekuni, Ma, Ji
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2012
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318935/
https://ncbi.nlm.nih.gov/pubmed/22479265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000334961
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