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Human CD14(hi) monocytes and myeloid dendritic cells provide a cell contact–dependent costimulatory signal for early CD40 ligand expression

CD40L on CD4(+) T cells plays a vital role in the activation of antigen-presenting cells, thus catalyzing a positive feedback loop for T-cell activation. Despite the pivotal juxtaposition of CD40L between antigen-presenting cells and T-cell activation, only a T-cell receptor stimulus is thought to b...

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Detalhes bibliográficos
Principais autores: Chakrabarty, Sagarika, Snyder, James T., Shen, Jijia, Azmi, Hooman, Hu, Paul Q., Chen, Qian, Ragheb, Jack A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318775/
https://ncbi.nlm.nih.gov/pubmed/20634374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-130252
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