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Human CD14(hi) monocytes and myeloid dendritic cells provide a cell contact–dependent costimulatory signal for early CD40 ligand expression
CD40L on CD4(+) T cells plays a vital role in the activation of antigen-presenting cells, thus catalyzing a positive feedback loop for T-cell activation. Despite the pivotal juxtaposition of CD40L between antigen-presenting cells and T-cell activation, only a T-cell receptor stimulus is thought to b...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3318775/ https://ncbi.nlm.nih.gov/pubmed/20634374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-130252 |
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