RACK1 Promotes Non-small-cell Lung Cancer Tumorigenicity through Activating Sonic Hedgehog Signaling Pathway

Non-small-cell lung cancer (NSCLC) is a deadly disease due to lack of effective diagnosis biomarker and therapeutic target. Much effort has been made in defining gene defects in NSCLC, but its full molecular pathogenesis remains unexplored. Here, we found RACK1 (receptor of activated kinase 1) was e...

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Dettagli Bibliografici
Autori principali: Shi, Shuo, Deng, Yue-Zhen, Zhao, Jiang-Sha, Ji, Xiao-Dan, Shi, Jun, Feng, Yu-Xiong, Li, Guo, Li, Jing-Jing, Zhu, Di, Koeffler, H. Phillip, Zhao, Yun, Xie, Dong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318742/
https://ncbi.nlm.nih.gov/pubmed/22262830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.315416
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