The Leukemia-associated Fusion Protein Tel-Platelet-derived Growth Factor Receptor β (Tel-PdgfRβ) Inhibits Transcriptional Repression of PTPN13 Gene by Interferon Consensus Sequence Binding Protein (Icsbp)

Icsbp is an interferon regulatory transcription factor with leukemia suppressor activity. In previous studies, we identified the gene encoding Fas-associated phosphatase 1 (Fap1; the PTPN13 gene) as an Icsbp target. In the current study, we determine that repression of PTPN13 by Icsbp requires coope...

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Main Authors: Huang, Weiqi, Hu, Liping, Bei, Ling, Hjort, Elizabeth, Eklund, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Gene Regulation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318728/
https://ncbi.nlm.nih.gov/pubmed/22262849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.294884
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