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Activity of the Mycobacterial Proteasomal ATPase Mpa Is Reversibly Regulated by Pupylation

Pupylation is a bacterial post-translational modification of target proteins on lysine residues with prokaryotic ubiquitin-like protein Pup. Pup-tagged substrates are recognized by a proteasome-interacting ATPase termed Mpa in Mycobacterium tuberculosis. Mpa unfolds pupylated substrates and threads...

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Bibliografske podrobnosti
Main Authors: Delley, Cyrille L., Striebel, Frank, Heydenreich, Franziska M., Özcelik, Dennis, Weber-Ban, Eilika
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318712/
https://ncbi.nlm.nih.gov/pubmed/22210775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.331124
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