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The mycobacterial Mpa–proteasome unfolds and degrades pupylated substrates by engaging Pup's N-terminus
Mycobacterium tuberculosis, along with other actinobacteria, harbours proteasomes in addition to members of the general bacterial repertoire of degradation complexes. In analogy to ubiquitination in eukaryotes, substrates are tagged for proteasomal degradation with prokaryotic ubiquitin-like protein...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857465/ https://ncbi.nlm.nih.gov/pubmed/20203624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.23 |
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