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Single-Dose Immunization with Virus Replicon Particles Confers Rapid Robust Protection against Rift Valley Fever Virus Challenge

Rift Valley fever virus (RVFV) causes outbreaks of severe disease in people and livestock throughout Africa and the Arabian Peninsula. The potential for RVFV introduction outside the area of endemicity highlights the need for fast-acting, safe, and efficacious vaccines. Here, we demonstrate a robust...

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Hlavní autoři: Dodd, Kimberly A., Bird, Brian H., Metcalfe, Maureen G., Nichol, Stuart T., Albariño, César G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318656/
https://ncbi.nlm.nih.gov/pubmed/22345465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.07104-11
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