RNA Synthesis by the Brome Mosaic Virus RNA-Dependent RNA Polymerase in Human Cells Reveals Requirements for De Novo Initiation and Protein-Protein Interaction

Brome mosaic virus (BMV) is a model positive-strand RNA virus whose replication has been studied in a number of surrogate hosts. In transiently transfected human cells, the BMV polymerase 2a activated signaling by the innate immune receptor RIG-I, which recognizes de novo-initiated non-self-RNAs. Ac...

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Detalhes bibliográficos
Main Authors: Subba-Reddy, Chennareddy V., Tragesser, Brady, Xu, Zhili, Stein, Barry, Ranjith-Kumar, C. T., Kao, C. Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318653/
https://ncbi.nlm.nih.gov/pubmed/22318148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00069-12
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