Enhanced Susceptibility of Ago1/3 Double-Null Mice to Influenza A Virus Infection

RNA interference (RNAi) is a critical component of many cellular antiviral responses in plants, invertebrates, and mammals. However, its in vivo role in host protection from the negative-sense RNA virus influenza virus type A (flu) is unclear. Here we have examined the role of RNAi in host defense t...

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Detalhes bibliográficos
Main Authors: Van Stry, Melanie, Oguin, Thomas H., Cheloufi, Sihem, Vogel, Peter, Watanabe, Makiko, Pillai, Meenu R., Dash, Pradyot, Thomas, Paul G., Hannon, Gregory J., Bix, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318639/
https://ncbi.nlm.nih.gov/pubmed/22318144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05303-11
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