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High Levels of Antibodies to Multiple Domains and Strains of VAR2CSA Correlate with the Absence of Placental Malaria in Cameroonian Women Living in an Area of High Plasmodium falciparum Transmission

Placental malaria, caused by sequestration of Plasmodium falciparum-infected erythrocytes in the placenta, is associated with increased risk of maternal morbidity and poor birth outcomes. The parasite antigen VAR2CSA (variant surface antigen 2-chondroitin sulfate A) is expressed on infected erythroc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tutterrow, Yeung L., Avril, Marion, Singh, Kavita, Long, Carole A., Leke, Robert J., Sama, Grace, Salanti, Ali, Smith, Joseph D., Leke, Rose G. F., Taylor, Diane W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318421/
https://ncbi.nlm.nih.gov/pubmed/22331427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00071-12
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