High Levels of Antibodies to Multiple Domains and Strains of VAR2CSA Correlate with the Absence of Placental Malaria in Cameroonian Women Living in an Area of High Plasmodium falciparum Transmission

Placental malaria, caused by sequestration of Plasmodium falciparum-infected erythrocytes in the placenta, is associated with increased risk of maternal morbidity and poor birth outcomes. The parasite antigen VAR2CSA (variant surface antigen 2-chondroitin sulfate A) is expressed on infected erythroc...

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Autori principali: Tutterrow, Yeung L., Avril, Marion, Singh, Kavita, Long, Carole A., Leke, Robert J., Sama, Grace, Salanti, Ali, Smith, Joseph D., Leke, Rose G. F., Taylor, Diane W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318421/
https://ncbi.nlm.nih.gov/pubmed/22331427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00071-12
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