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Infection with Anaplasma phagocytophilum Activates the Phosphatidylinositol 3-Kinase/Akt and NF-κB Survival Pathways in Neutrophil Granulocytes

Anaplasma phagocytophilum, a Gram-negative, obligate intracellular bacterium infects primarily neutrophil granulocytes. Infection with A. phagocytophilum leads to inhibition of neutrophil apoptosis and consequently contributes to the longevity of the host cells. Previous studies demonstrated that th...

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Autori principali: Sarkar, Arup, Hellberg, Lars, Bhattacharyya, Asima, Behnen, Martina, Wang, Keqing, Lord, Janet M., Möller, Sonja, Kohler, Maja, Solbach, Werner, Laskay, Tamás
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318406/
https://ncbi.nlm.nih.gov/pubmed/22252875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05219-11
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