Infection with Anaplasma phagocytophilum Activates the Phosphatidylinositol 3-Kinase/Akt and NF-κB Survival Pathways in Neutrophil Granulocytes

Anaplasma phagocytophilum, a Gram-negative, obligate intracellular bacterium infects primarily neutrophil granulocytes. Infection with A. phagocytophilum leads to inhibition of neutrophil apoptosis and consequently contributes to the longevity of the host cells. Previous studies demonstrated that th...

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Autors principals: Sarkar, Arup, Hellberg, Lars, Bhattacharyya, Asima, Behnen, Martina, Wang, Keqing, Lord, Janet M., Möller, Sonja, Kohler, Maja, Solbach, Werner, Laskay, Tamás
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318406/
https://ncbi.nlm.nih.gov/pubmed/22252875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05219-11
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