Impairment of Gamma Interferon Signaling in Human Neutrophils Infected with Anaplasma phagocytophilum

Anaplasma phagocytophilum, the causative agent of tick-borne human granulocytic anaplasmosis (HGA), is an intracellular bacterium which survives and multiplies inside polymorphonuclear neutrophil granulocytes (PMN). Increased bacterial burden in gamma interferon (IFN-γ)-deficient mice suggested a ma...

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Auteurs principaux: Bussmeyer, Uta, Sarkar, Arup, Broszat, Kirsten, Lüdemann, Tanja, Möller, Sonja, van Zandbergen, Ger, Bogdan, Christian, Behnen, Martina, Dumler, J. Stephen, von Loewenich, Friederike D., Solbach, Werner, Laskay, Tamás
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
Sujets:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798180/
https://ncbi.nlm.nih.gov/pubmed/19858302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01005-09
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