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Optimal Meropenem Concentrations To Treat Multidrug-Resistant Pseudomonas aeruginosa Septic Shock

A patient with septic shock due to extensively drug resistant (XDR) Pseudomonas aeruginosa was cured by optimizing the meropenem (MEM) regimen to obtain at least 40% of the time between two administrations in which drug levels were four times higher than the MIC of the pathogen. As the standard drug...

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Main Authors: Taccone, Fabio Silvio, Cotton, Frédéric, Roisin, Sandrine, Vincent, Jean-Louis, Jacobs, Frédérique
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318384/
https://ncbi.nlm.nih.gov/pubmed/22290984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06389-11
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