Single- and Multiple-Ascending-Dose Studies of the NS3 Protease Inhibitor Asunaprevir in Subjects with or without Chronic Hepatitis C

Hepatitis C virus (HCV) protease inhibitors combined with pegylated alfa interferon-ribavirin have demonstrated improved efficacy compared with pegylated alfa interferon-ribavirin alone for the treatment of chronic hepatitis C. Asunaprevir (BMS-650032), a novel HCV NS3 protease inhibitor in clinical...

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Hlavní autoři: Pasquinelli, Claudio, McPhee, Fiona, Eley, Timothy, Villegas, Criselda, Sandy, Katrina, Sheridan, Pamela, Persson, Anna, Huang, Shu-Pang, Hernandez, Dennis, Sheaffer, Amy K., Scola, Paul, Marbury, Thomas, Lawitz, Eric, Goldwater, Ronald, Rodriguez-Torres, Maribel, DeMicco, Michael, Wright, David, Charlton, Michael, Kraft, Walter K., Lopez-Talavera, Juan-Carlos, Grasela, Dennis M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318341/
https://ncbi.nlm.nih.gov/pubmed/22290978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05854-11
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