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Temporal Interplay between Efflux Pumps and Target Mutations in Development of Antibiotic Resistance in Escherichia coli

The emergence of resistance presents a debilitating change in the management of infectious diseases. Currently, the temporal relationship and interplay between various mechanisms of drug resistance are not well understood. A thorough understanding of the resistance development process is needed to f...

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Autori principali: Singh, Renu, Swick, Michelle C., Ledesma, Kimberly R., Yang, Zhen, Hu, Ming, Zechiedrich, Lynn, Tam, Vincent H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318314/
https://ncbi.nlm.nih.gov/pubmed/22232279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05693-11
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