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Wsp1 Is Downstream of Cin1 and Regulates Vesicle Transport and Actin Cytoskeleton as an Effector of Cdc42 and Rac1 in Cryptococcus neoformans

Human Wiskott-Aldrich syndrome protein (WASP) is a scaffold linking upstream signals to the actin cytoskeleton. In response to intersectin ITSN1 and Rho GTPase Cdc42, WASP activates the Arp2/3 complex to promote actin polymerization. The human pathogen Cryptococcus neoformans contains the ITSN1 homo...

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Hlavní autoři: Shen, Gui, Zhou, Erxun, Alspaugh, J. Andrew, Wang, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318296/
https://ncbi.nlm.nih.gov/pubmed/22327008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00011-12
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