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Ras1 Acts through Duplicated Cdc42 and Rac Proteins to Regulate Morphogenesis and Pathogenesis in the Human Fungal Pathogen Cryptococcus neoformans

Proliferation and morphogenesis in eukaryotic cells depend on the concerted activity of Rho-type GTPases, including Ras, Cdc42, and Rac. The sexually dimorphic fungus Cryptococcus neoformans, which encodes paralogous, non-essential copies of all three, provides a unique model in which to examine the...

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Detalhes bibliográficos
Main Authors: Ballou, Elizabeth Ripley, Kozubowski, Lukasz, Nichols, Connie B., Alspaugh, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738472/
https://ncbi.nlm.nih.gov/pubmed/23950731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003687
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