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Direct construction of a chromosome-specific NotI linking library from flow-sorted chromosomes.

A linking library consists of genomic DNA fragments which contain a specific rare restriction enzyme site; such clones are very useful as probes in pulsed field gel electrophoresis and in mapping and cloning large regions of DNA. However, identifying those linking clones which map to a certain chrom...

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Detalhes bibliográficos
Main Authors: Wallace, M R, Fountain, J W, Brereton, A M, Collins, F S
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC331827/
https://ncbi.nlm.nih.gov/pubmed/2784207
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