Killed but Metabolically Active Leishmania infantum as a Novel Whole-Cell Vaccine for Visceral Leishmaniasis

There are currently no effective vaccines for visceral leishmaniasis, the second most deadly parasitic infection in the world. Here, we describe a novel whole-cell vaccine approach using Leishmania infantum chagasi promastigotes treated with the psoralen compound amotosalen (S-59) and low doses of U...

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Bibliografische gegevens
Hoofdauteurs: Bruhn, Kevin W., Birnbaum, Ron, Haskell, Jacquelyn, Vanchinathan, Veena, Greger, Stephanie, Narayan, Rupa, Chang, Pei-Lin, Tran, Thu Anh, Hickerson, Suzanne M., Beverley, Stephen M., Wilson, Mary E., Craft, Noah
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
Onderwerpen:
Vaccines
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318268/
https://ncbi.nlm.nih.gov/pubmed/22323556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05660-11
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