LXR Deficiency Confers Increased Protection against Visceral Leishmania Infection in Mice

BACKGROUND: The liver X receptors (LXRs) are a family of nuclear receptor transcription factors that are activated by oxysterols and have defined roles in both lipid metabolism and cholesterol regulation. LXRs also affect antimicrobial responses and have anti-inflammatory effects in macrophages. As...

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Detalhes bibliográficos
Main Authors: Bruhn, Kevin W., Marathe, Chaitra, Maretti-Mira, Ana Cláudia, Nguyen, Hong, Haskell, Jacquelyn, Tran, Thu Anh, Vanchinathan, Veena, Gaur, Upasna, Wilson, Mary E., Tontonoz, Peter, Craft, Noah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2982826/
https://ncbi.nlm.nih.gov/pubmed/21103366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000886
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