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Protein-DNA conjugates produced by UV irradiation and their use as probes for hybridization.
Several proteins have been crosslinked to DNA by low dose uv irradiation. The principle of the method is based on an efficient and fast radiation induced reaction of amino acid residues with DNA at low pH. The method seems to be of general applicability for crosslinking proteins to DNA in a very sim...
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| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1989
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC331822/ https://ncbi.nlm.nih.gov/pubmed/2922287 |
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