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Synthetic repeating sequence DNAs containing phosphorothioates: nuclease sensitivity and triplex formation.

More than twenty repeating sequence DNAs containing phosphorothioates were prepared from the appropriate dXTPs with DNA polymerase I. The Tms of the modified DNAs were all lower than the parent polymers. A phosphorothioate group 5' to a pyrimidine gave rise to a large decrease than 5' to a...

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Detalles Bibliográficos
Main Authors: Latimer, L J, Hampel, K, Lee, J S
Formato: Artigo
Idioma:Inglês
Publicado: 1989
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC331821/
https://ncbi.nlm.nih.gov/pubmed/2922286
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