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Synthetic repeating sequence DNAs containing phosphorothioates: nuclease sensitivity and triplex formation.

More than twenty repeating sequence DNAs containing phosphorothioates were prepared from the appropriate dXTPs with DNA polymerase I. The Tms of the modified DNAs were all lower than the parent polymers. A phosphorothioate group 5' to a pyrimidine gave rise to a large decrease than 5' to a...

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Main Authors: Latimer, L J, Hampel, K, Lee, J S
格式: Artigo
語言:Inglês
出版: 1989
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC331821/
https://ncbi.nlm.nih.gov/pubmed/2922286
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