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Release of mitochondrial apoptogenic factors and cell death are mediated by CK2 and NADPH oxidase
Activation of the NADPH oxidase subunit, NOX2, and increased oxidative stress are associated with neuronal death after cerebral ischemia and reperfusion. Inhibition of NOX2 by casein kinase 2 (CK2) leads to neuronal survival, but the mechanism is unknown. In this study, we show that in copper/zinc-s...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3318149/ https://ncbi.nlm.nih.gov/pubmed/22146192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.176 |
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