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The utility of (11)C-arachidonate PET to study in vivo dopaminergic neurotransmission in humans

We developed a novel method to study dopaminergic neurotransmission using positron emission tomography (PET) with [1-(11)C]arachidonic acid ([1-(11)C]AA). Previous preclinical studies have shown the utility of [1-(11)C]AA as a marker of signal transduction coupled to cytosolic phospholipase A(2) (cP...

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Bibliografiske detaljer
Main Authors: Thambisetty, Madhav, Gallardo, Kathy A, Liow, Jeih-San, Beason-Held, Lori L, Umhau, John C, Bhattacharjee, Abesh K, Der, Margaret, Herscovitch, Peter, Rapoport, Judith L, Rapoport, Stanley I
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318145/
https://ncbi.nlm.nih.gov/pubmed/22167235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.171
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