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Is a Malleable Protein Necessarily Highly Dynamic? The Hydrophobic Core of the Nuclear Coactivator Binding Domain Is Well Ordered
The nuclear coactivator binding domain of CREB binding protein folds into remarkably different structures in complex with different ligands. To understand the mechanism of the structural adaptability in the nuclear coactivator binding domain (NCBD), we have compared the dynamics of the hydrophobic c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3318130/ https://ncbi.nlm.nih.gov/pubmed/22500763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.02.014 |
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