Imaging Nanometer-Sized α-Synuclein Aggregates by Superresolution Fluorescence Localization Microscopy

The morphological features of α-synuclein (AS) amyloid aggregation in vitro and in cells were elucidated at the nanoscale by far-field subdiffraction fluorescence localization microscopy. Labeling AS with rhodamine spiroamide probes allowed us to image AS fibrillar structures by fluorescence stochas...

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Bibliographische Detailangaben
Hauptverfasser: Roberti, M. Julia, Fölling, Jonas, Celej, M. Soledad, Bossi, Mariano, Jovin, Thomas M., Jares-Erijman, Elizabeth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2012
Schlagworte:
Protein
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318128/
https://ncbi.nlm.nih.gov/pubmed/22500760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.010
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