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Supramolecular Non-Amyloid Intermediates in the Early Stages of α-Synuclein Aggregation
The aggregation of α-synuclein is associated with progression of Parkinson's disease. We have identified submicrometer supramolecular structures that mediate the early stages of the overall mechanism. The sequence of structural transformations between metastable intermediates were captured and...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Biophysical Society
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3296045/ https://ncbi.nlm.nih.gov/pubmed/22404935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.01.051 |
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