MicroRNA-143 is a critical regulator of cell cycle activity in stem cells with co-overexpression of Akt and angiopoietin-1 via transcriptional regulation of Erk5/cyclin D1 signaling

We report that simultaneous expression of Akt and angiopoietin-1 (Ang-1) transgenes supported mitogenesis in stem cells with a critical role for microRNA-143 (miR-143) downstream of FoxO1 transcription factor. Mesenchymal stem cells (MSC) from young male rats were transduced with Ad-vectors encoding...

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Main Authors: Lai, Vien Khach, Ashraf, Muhammad, Jiang, Shujia, Haider, Khawaja Husnain
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318108/
https://ncbi.nlm.nih.gov/pubmed/22374674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.4.19211
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