A Human PrM Antibody That Recognizes a Novel Cryptic Epitope on Dengue E Glycoprotein

Dengue virus (DENV) is a major mosquito-borne pathogen infecting up to 100 million people each year; so far no effective treatment or vaccines are available. Recently, highly cross-reactive and infection-enhancing pre-membrane (prM)-specific antibodies were found to dominate the anti-DENV immune res...

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Hauptverfasser: Chan, Annie Hoi Yi, Tan, Hwee Cheng, Chow, Angelia Yee, Lim, Angeline Pei Chiew, Lok, Shee Mei, Moreland, Nicole J., Vasudevan, Subhash G., MacAry, Paul A., Ooi, Eng Eong, Hanson, Brendon J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317930/
https://ncbi.nlm.nih.gov/pubmed/22509258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033451
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