Poly (ADP-ribose) polymerase plays an important role in intermittent hypoxia-induced cell death in rat cerebellar granule cells

BACKGROUND: Episodic cessation of airflow during sleep in patients with sleep apnea syndrome results in intermittent hypoxia (IH). Our aim was to investigate the effects of IH on cerebellar granule cells and to identify the mechanism of IH-induced cell death. METHODS: Cerebellar granule cells were f...

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Autori principali: Chiu, Sheng-Chun, Huang, Sung-Ying, Tsai, Yu-Chieh, Chen, Shee-Ping, Pang, Cheng-Yoong, Lien, Chih-Feng, Lin, Yu-Jou, Yang, Kun-Ta
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317837/
https://ncbi.nlm.nih.gov/pubmed/22405498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-29
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